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Structural requirements of thiol compounds in the inhibition of human liver iodothyronine 5'-deiodinase.

2-Thiouracil and a number of its alkyl derivatives are known to inhibit the enzymic 5'-deodination of thyroxine to 3,5,3'-tri-iodothyronine. The structural requirements for inhibition of iodothyronine 5'-deiodinase were investigated by using a washed postmitochondrial particulate frac...

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Detalles Bibliográficos
Main Authors: Harbottle, R, Richardson, S J
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1153240/
https://ncbi.nlm.nih.gov/pubmed/6696743
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