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Two different protein kinase activities are associated with the insulin receptor.

In intact rat hepatocytes insulin stimulates the phosphorylation of the beta-subunit of its receptor exclusively on serine residues, which are also phosphorylated in the absence of insulin. In contrast, in partially purified insulin receptors derived from these same cells and in highly purified insu...

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Main Authors: Gazzano, H, Kowalski, A, Fehlmann, M, Van Obberghen, E
格式: Artigo
語言:Inglês
出版: 1983
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152548/
https://ncbi.nlm.nih.gov/pubmed/6199015
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