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Empirical characterization of the expression ratio noise structure in high-density oligonucleotide arrays

BACKGROUND: High-density oligonucleotide arrays (HDONAs) are a powerful tool for assessing differential mRNA expression levels. To establish the statistical significance of an observed change in expression, one must take into account the noise introduced by the enzymatic and hybridization steps, cal...

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Detalhes bibliográficos
Main Authors: Naef, Felix, Hacker, Coleen R, Patil, Nila, Magnasco, Marcelo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115253/
https://ncbi.nlm.nih.gov/pubmed/11983059
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