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The storage products in genetic and swainsonine-induced human mannosidosis.

Swainsonine induces the accumulation of mannose-rich oligosaccharides in human fibroblasts. The composition of the storage products shows that swainsonine completely inhibits lysosomal alpha-D-mannosidase and alters processing of glycoproteins by inhibiting Golgi alpha-D-mannosidase II. Comparison o...

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Main Authors: Cenci di Bello, I, Dorling, P, Winchester, B
格式: Artigo
語言:Inglês
出版: 1983
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152453/
https://ncbi.nlm.nih.gov/pubmed/6419731
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