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CHOP gene expression in response to endoplasmic-reticular stress requires NFY interaction with different domains of a conserved DNA-binding element

The transcription factor CHOP/GADD153 gene is induced by cellular stress and is involved in mediating apoptosis. We report the identification of a conserved region in the promoter of the CHOP gene responsible for its inducibility by endoplasmic reticulum (ER) stress. Deletion mutants of the human CH...

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Autors principals: Ubeda, Mariano, Habener, Joel F.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC115245/
https://ncbi.nlm.nih.gov/pubmed/11121490
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