Llwytho...

The SP1 sites of the human apoCIII enhancer are essential for the expression of the apoCIII gene and contribute to the hepatic and intestinal expression of the apoA-I gene in transgenic mice

We have generated transgenic mice carrying wild-type and mutant forms of the apolipoprotein (apo)A-I/apoCIII gene cluster. Mutations were introduced either in one or in three SP1 binding sites of the apoCIII enhancer. In mice carrying the wild-type transgene, major sites of apoA-I mRNA synthesis wer...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Georgopoulos, Spiros, Kan, Horng-Yuan, Reardon-Alulis, Catherine, Zannis, Vassilis
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC115241/
https://ncbi.nlm.nih.gov/pubmed/11121483
Tagiau: Ychwanegu Tag
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