How many replicates of arrays are required to detect gene expression changes in microarray experiments? A mixture model approach

BACKGROUND: It has been recognized that replicates of arrays (or spots) may be necessary for reliably detecting differentially expressed genes in microarray experiments. However, the often-asked question of how many replicates are required has barely been addressed in the literature. In general, the...

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Bibliografiske detaljer
Main Authors: Pan, Wei, Lin, Jizhen, Le, Chap T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2002
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC115224/
https://ncbi.nlm.nih.gov/pubmed/12049663
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