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The macromolecular structure of human cervical-mucus glycoproteins. Studies on fragments obtained after reduction of disulphide bridges and after subsequent trypsin digestion.

Human cervical-mucus glycoproteins (mucins) were extracted with 6 M-guanidinium chloride in the presence of proteinase inhibitors and purified by isopycnic density-gradient centrifugation. The whole mucins (Mr approx. 10 X 10(6] were degraded into 'subunits' (Mr approx. 2 X 10(6] by reduct...

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Autori principali: Carlstedt, I, Lindgren, H, Sheehan, J K
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1983
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1152144/
https://ncbi.nlm.nih.gov/pubmed/6615445
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