Evolutionary conservation of otd/Otx2 transcription factor action: a genome-wide microarray analysis in Drosophila

BACKGROUND: Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the Drosophila otd gene and orthologous mammalian Otx genes are functionally equivalent, in that overexpression of either gene in null...

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Main Authors: Montalta-He, Haiqiong, Leemans, Ronny, Loop, Thomas, Strahm, Martin, Certa, Ulrich, Primig, Michael, Acampora, Dario, Simeone, Antonio, Reichert, Heinrich
Format: Artigo
Language:Inglês
Published: BioMed Central 2002
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC115189/
https://ncbi.nlm.nih.gov/pubmed/11983056
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