Rational Design of a Corynebacterium glutamicum Pantothenate Production Strain and Its Characterization by Metabolic Flux Analysis and Genome-Wide Transcriptional Profiling

A “second-generation” production strain was derived from a Corynebacterium glutamicum pantothenate producer by rational design to assess its potential to synthesize and accumulate the vitamin pantothenate by batch cultivation. The new pantothenate production strain carries a deletion of the ilvA gen...

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Detalhes bibliográficos
Main Authors: Hüser, Andrea T., Chassagnole, Christophe, Lindley, Nic D., Merkamm, Muriel, Guyonvarch, Armel, Elišáková, Veronika, Pátek, Miroslav, Kalinowski, Jörn, Brune, Iris, Pühler, Alfred, Tauch, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Physiology and Biotechnology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151861/
https://ncbi.nlm.nih.gov/pubmed/15933028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.6.3255-3268.2005
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