Aspergillus parasiticus Cyclase Catalyzes Two Dehydration Steps in Aflatoxin Biosynthesis

In the aflatoxin biosynthetic pathway, 5′-oxoaverantin (OAVN) cyclase, the cytosolic enzyme, catalyzes the reaction from OAVN to (2′S,5′S)-averufin (AVR) (E. Sakuno, K. Yabe, and H. Nakajima, Appl. Environ. Microbiol. 69:6418-6426, 2003). Interestingly, the N-terminal 25-amino-acid sequence of OAVN...

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Bibliografiske detaljer
Main Authors: Sakuno, Emi, Wen, Ying, Hatabayashi, Hidemi, Arai, Hatsue, Aoki, Chiemi, Yabe, Kimiko, Nakajima, Hiromitsu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Mycology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151850/
https://ncbi.nlm.nih.gov/pubmed/15932995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.6.2999-3006.2005
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