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Homocysteine Toxicity in Escherichia coli Is Caused by a Perturbation of Branched-Chain Amino Acid Biosynthesis

In Escherichia coli the sulfur-containing amino acid homocysteine (Hcy) is the last intermediate on the methionine biosynthetic pathway. Supplementation of a glucose-based minimal medium with Hcy at concentrations greater than 0.2 mM causes the growth of E. coli Frag1 to be inhibited. Supplementatio...

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Hlavní autoři: Tuite, Nina L., Fraser, Katy R., O'Byrne, Conor P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151774/
https://ncbi.nlm.nih.gov/pubmed/15968045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.13.4362-4371.2005
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