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Expression Levels Influence Ribosomal Frameshifting at the Tandem Rare Arginine Codons AGG_AGG and AGA_AGA in Escherichia coli

The rare codons AGG and AGA comprise 2% and 4%, respectively, of the arginine codons of Escherichia coli K-12, and their cognate tRNAs are sparse. At tandem occurrences of either rare codon, the paucity of cognate aminoacyl tRNAs for the second codon of the pair facilitates peptidyl-tRNA shifting to...

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Autori principali: Gurvich, Olga L., Baranov, Pavel V., Gesteland, Raymond F., Atkins, John F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151738/
https://ncbi.nlm.nih.gov/pubmed/15937165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.12.4023-4032.2005
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