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Effect of carboxylic acid xenobiotics and their metabolites on the activity of carnitine acyltransferases.

Salicylyl-CoA and benzoyl-CoA were good inhibitors of carnitine acetyltransferase (CAT), competing with acetyl-CoA with Ki values of 7.5 and 22 microM respectively in the forward direction and with CoA in the reverse reaction with similar Ki values. They were also competitive inhibitors of carnitine...

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Detalhes bibliográficos
Main Authors: Vessey, D A, Chen, W W, Ramsay, R R
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151530/
https://ncbi.nlm.nih.gov/pubmed/1953685
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