Structural and Functional Relationship between the Receptor Recognition and Neuraminidase Activities of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein: Receptor Recognition Is Dependent on Neuraminidase Activity

The terminal globular domain of the paramyxovirus hemagglutinin-neuraminidase (HN) glycoprotein spike has a number of conserved residues that are predicted to form its neuraminidase (NA) active site, by analogy to the influenza virus neuraminidase protein. We have performed a site-directed mutationa...

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Autores principales: Iorio, Ronald M., Field, Gisela M., Sauvron, Jennifer M., Mirza, Anne M., Deng, Ruitang, Mahon, Paul J., Langedijk, Johannes P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC115138/
https://ncbi.nlm.nih.gov/pubmed/11160691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1918-1927.2001
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