Peptides Corresponding to the Heptad Repeat Motifs in the Transmembrane Protein (gp41) of Human Immunodeficiency Virus Type 1 Elicit Antibodies to Receptor-Activated Conformations of the Envelope Glycoprotein

Two heptad repeat regions in the ectodomain of the human immunodeficiency virus type 1 (HIV-1) transmembrane subunit (gp41) self-assemble into a six-helix bundle structure that is critical for virus entry. Immunizations with peptides corresponding to these regions generated antibodies specific to th...

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Bibliographische Detailangaben
Hauptverfasser: de Rosny, Eve, Vassell, Russell, Wingfield, Paul T., Wild, Carl T., Weiss, Carol D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC115132/
https://ncbi.nlm.nih.gov/pubmed/11507232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8859-8863.2001
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