Cytopathicity of Human Immunodeficiency Virus Type 1 Primary Isolates Depends on Coreceptor Usage and Not Patient Disease Status

It has been hypothesized that human immunodeficiency virus type 1 (HIV-1) evolves toward increased cytopathicity in conjunction with disease progression in infected patients. A viral property known to evolve in some but not all patients is coreceptor utilization, and it has been shown that a switch...

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Main Authors: Kreisberg, Jason F., Kwa, David, Schramm, Birgit, Trautner, Verena, Connor, Ruth, Schuitemaker, Hanneke, Mullins, James I., van't Wout, Angélique B., Goldsmith, Mark A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC115129/
https://ncbi.nlm.nih.gov/pubmed/11507229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8842-8847.2001
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