Effects of hypothyroidism and high-fat feeding on mRNA concentrations for the low-density-lipoprotein receptor and on acyl-CoA:cholesterol acyltransferase activities in rat liver.

1. Induction of hypothyroidism in rats by feeding propylthiouracil (PTU) significantly increased serum cholesterol concentrations, and the effect was more pronounced for cholesterol in low-density lipoproteins (LDL) rather than high-density lipoproteins (HDL). The concentrations of serum triacylglyc...

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Detalhes bibliográficos
Main Authors: Salter, A M, Hayashi, R, al-Seeni, M, Brown, N F, Bruce, J, Sorensen, O, Atkinson, E A, Middleton, B, Bleackley, R C, Brindley, D N
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1151078/
https://ncbi.nlm.nih.gov/pubmed/2064617
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