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Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast

In eukaryotes, entry into mitosis is induced by cyclin B-bound Cdk1, which is held in check by the protein kinase, Wee1. In budding yeast, Swe1 (Wee1 ortholog) is targeted to the bud neck through Hsl1 (Nim1-related kinase) and its adaptor Hsl7, and is hyperphosphorylated prior to ubiquitin-mediated...

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Main Authors: Asano, Satoshi, Park, Jung-Eun, Sakchaisri, Krisada, Yu, Li-Rong, Song, Sukgil, Supavilai, Porntip, Veenstra, Timothy D, Lee, Kyung S
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150880/
https://ncbi.nlm.nih.gov/pubmed/15920482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600683
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