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Concerted mechanism of Swe1/Wee1 regulation by multiple kinases in budding yeast
In eukaryotes, entry into mitosis is induced by cyclin B-bound Cdk1, which is held in check by the protein kinase, Wee1. In budding yeast, Swe1 (Wee1 ortholog) is targeted to the bud neck through Hsl1 (Nim1-related kinase) and its adaptor Hsl7, and is hyperphosphorylated prior to ubiquitin-mediated...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1150880/ https://ncbi.nlm.nih.gov/pubmed/15920482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600683 |
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