Feline Leukemia Virus DNA Vaccine Efficacy Is Enhanced by Coadministration with Interleukin-12 (IL-12) and IL-18 Expression Vectors

The expectation that cell-mediated immunity is important in the control of feline leukemia virus (FeLV) infection led us to test a DNA vaccine administered alone or with cytokines that favored the development of a Th1 immune response. The vaccine consisted of two plasmids, one expressing the gag/pol...

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Autores principales: Hanlon, Linda, Argyle, David, Bain, Derek, Nicolson, Lesley, Dunham, Stephen, Golder, Matthew C., McDonald, Michael, McGillivray, Christine, Jarrett, Oswald, Neil, James C., Onions, David E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC115087/
https://ncbi.nlm.nih.gov/pubmed/11507187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.18.8424-8433.2001
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