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Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway

LIS1 and nuclear distribution gene E (NudE) are partner proteins in a conserved pathway regulating the function of dynein and microtubules. Here, we present data that cytoplasmic LEK1 (cytLEK1), a large protein containing a spectrin repeat and multiple leucine zippers, is a component of this pathway...

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Main Authors: Soukoulis, Victor, Reddy, Samyukta, Pooley, Ryan D., Feng, Yuanyi, Walsh, Christopher A., Bader, David M.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150833/
https://ncbi.nlm.nih.gov/pubmed/15939891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502303102
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