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Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors

The prevalence of alternative splicing as a target for alterations leading to human genetic disorders makes it highly relevant for therapy. Here we have used in vitro splicing reactions with different splicing reporter constructs to screen 4,000 chemical compounds for their ability to selectively in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Soret, Johann, Bakkour, Nadia, Maire, Sophie, Durand, Sébastien, Zekri, Latifa, Gabut, Mathieu, Fic, Weronika, Divita, Gilles, Rivalle, Christian, Dauzonne, Daniel, Nguyen, Chi Hung, Jeanteur, Philippe, Tazi, Jamal
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2005
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150812/
https://ncbi.nlm.nih.gov/pubmed/15939885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409829102
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