Simultaneous Positive and Purifying Selection on Overlapping Reading Frames of the tat and vpr Genes of Simian Immunodeficiency Virus

Tat-specific cytotoxic T cells have previously been shown to exert positive Darwinian selection favoring amino acid replacements of an epitope of simian immunodeficiency virus (SIV). The region of the tat gene encoding this epitope falls within a region of overlap between the tat and vpr reading fra...

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Detalhes bibliográficos
Main Authors: Hughes, Austin L., Westover, Kristi, da Silva, Jack, O'Connor, David H., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Recombination and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115040/
https://ncbi.nlm.nih.gov/pubmed/11483741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.7966-7972.2001
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