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Posttranslational Processing of Infected Cell Proteins 0 and 4 of Herpes Simplex Virus 1 Is Sequential and Reflects the Subcellular Compartment in Which the Proteins Localize

The herpes simplex virus 1 (HSV-1) infected cell proteins 0 and 4 (ICP0 and ICP4) are multifunctional proteins extensively posttranscriptionally processed by both cellular and viral enzymes. We examined by two-dimensional separations the posttranslational forms of ICP0 and ICP4 in HEp-2 cells and in...

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Autori principali: Advani, Sunil J., Hagglund, Ryan, Weichselbaum, Ralph R., Roizman, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC115034/
https://ncbi.nlm.nih.gov/pubmed/11483735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.7904-7912.2001
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