Immunization with a Pentameric L1 Fusion Protein Protects against Papillomavirus Infection

The prophylactic papillomavirus vaccines currently in clinical trials are composed of viral L1 capsid protein that is synthesized in eukaryotic expression systems and purified in the form of virus-like particles (VLPs). To evaluate whether VLPs are necessary for effective vaccination, we expressed t...

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Detalhes bibliográficos
Main Authors: Yuan, Hang, Estes, Patricia A., Chen, Yan, Newsome, Joseph, Olcese, Vanessa A., Garcea, Robert L., Schlegel, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115027/
https://ncbi.nlm.nih.gov/pubmed/11483728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.7848-7853.2001
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