Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor.

The biochemical and morphological consequences of procollagen prolyl 4-hydroxylase inhibition by pyridine-2,4-dicarboxylic acid (2,4-PDCA) and its diethyl ester (diethyl-2,4-PDC) were studied in chick-embryo calvaria, which predominantly synthesize type I collagen. Half-maximal inhibition of tissue...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Tschank, G, Brocks, D G, Engelbart, K, Mohr, J, Baader, E, Günzler, V, Hanauske-Abel, H M
פורמט: Artigo
שפה:Inglês
יצא לאור: 1991
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150076/
https://ncbi.nlm.nih.gov/pubmed/1850989
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