Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated.

Some investigators have described the presence in Alzheimer's disease brain extracts of several abnormal forms of the microtubule-associated protein tau, based on their unusual mobility in SDS/PAGE. It has been proposed that these abnormal forms of tau may be the result of aberrant tau phosphor...

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Autores principales: Hanger, D P, Brion, J P, Gallo, J M, Cairns, N J, Luthert, P J, Anderton, B H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1150018/
https://ncbi.nlm.nih.gov/pubmed/1826835
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