Binding of Human Immunodeficiency Virus Type 1 gp120 to CXCR4 Induces Mitochondrial Transmembrane Depolarization and Cytochrome c-Mediated Apoptosis Independently of Fas Signaling

Apoptosis of CD4(+) T lymphocytes, induced by contact between human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (gp120) and its receptors, could contribute to the cell depletion observed in HIV-infected individuals. CXCR4 appears to play an important role in gp120-induced cell death,...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Roggero, Rodolphe, Robert-Hebmann, Véronique, Harrington, Steve, Roland, Joachim, Vergne, Laurence, Jaleco, Sara, Devaux, Christian, Biard-Piechaczyk, Martine
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2001
Fag:	Virus-Cell Interactions
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11462036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.16.7637-7650.2001
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!