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alpha-L-iduronidase in normal and mucopolysaccharidosis-type-I human skin fibroblasts.

alpha-L-Iduronidase synthesis and maturation were analysed in fibroblasts from normal controls and from alpha-L-iduronidase-deficient mucopolysaccharidosis-type-I (MPS-I) patients. Fibroblasts were radiolabelled with [3H]leucine and alpha-L-iduronidase was isolated from cell lysates or culture mediu...

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Detalhes bibliográficos
Main Authors: Taylor, J A, Gibson, G J, Brooks, D A, Hopwood, J J
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149947/
https://ncbi.nlm.nih.gov/pubmed/1900419
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