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Glucagon and ammonia influence the long-term regulation of phosphate-dependent glutaminase activity in primary cultures of rat hepatocytes.

1. Glutaminase activity was measured in primary cultures of hepatocytes. 2. Enzyme activity decreased markedly after 24-40 h in culture, and this loss of activity was accompanied by loss of enzyme protein. 3. The loss of activity was delayed by high concentrations of glutamine, and was abolished by...

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Detalhes bibliográficos
Main Authors: McGivan, J D, Boon, K, Doyle, F A
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149926/
https://ncbi.nlm.nih.gov/pubmed/2001224
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