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Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide.
Mixtures of Cu2+ and H2O2 at pH 7.4 caused damage to the bases in DNA greater than that caused by mixtures of Fe3+ and H2O2. Addition of ascorbic acid to the Cu2+/H2O2 system caused a very large increase in base damage, much greater than that produced by the Fe3+/H2O2/ascorbic acid system. The produ...
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主要な著者: | , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
1991
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1149805/ https://ncbi.nlm.nih.gov/pubmed/1899997 |
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