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Reconstitution of a Functional Duck Hepatitis B Virus Replication Initiation Complex from Separate Reverse Transcriptase Domains Expressed in Escherichia coli
Hepatitis B viruses replicate through reverse transcription of an RNA intermediate, the pregenomic RNA (pgRNA). Replication is initiated de novo and requires formation of a ribonucleoprotein complex comprising the viral reverse transcriptase (P protein), an RNA stem-loop structure (ɛ) on the pgRNA,...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2001
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114976/ https://ncbi.nlm.nih.gov/pubmed/11462013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7410-7419.2001 |
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