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Both endocytic and endogenous protein degradation in fibroblasts is stimulated by serum/amino acid deprivation and inhibited by 3-methyladenine.

Incubation of BHK-21 hamster fibroblasts in a serum- and amino acid-deficient medium caused a 3-fold increase in the degradation of endogenous protein, a doubling of the degradation of endocytosed epidermal growth factor, and an eightfold increase in the degradation of endocytosed alpha 2-macroglobu...

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Dettagli Bibliografici
Autori principali: Hendil, K B, Lauridsen, A M, Seglen, P O
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149747/
https://ncbi.nlm.nih.gov/pubmed/1702625
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