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The herpes simplex virus protein Vmw65 can trans-activate both viral and cellular promoters in neuronal cells.

Transcription of the herpes simplex virus (HSV) immediate-early (IE) genes in lytic infection is dependent upon the formation of a complex between the cellular transcription factor Oct-1 and the HSV virion protein Vmw65. This complex then binds to the TAATGARAT sequence in the IE promoters and trans...

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Autors principals: Estridge, J K, Kemp, L M, Latchman, D S
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149545/
https://ncbi.nlm.nih.gov/pubmed/2171502
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