Determination of Essential Amino Acids Involved in the CD4-Independent Tropism of the X4 Human Immunodeficiency Virus Type 1 m7NDK Isolate: Role of Potential N Glycosylations in the C2 and V3 Regions of gp120

Seven mutations in the C2, V3, and C3 regions of gp120 are implicated in the tropism of the first CD4-independent human immunodeficiency virus type 1 isolate, m7NDK. Site-directed mutagenesis revealed that three amino acids are essential to maintain this tropism, one in the C2 region and two in the...

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Main Authors: Dumonceaux, Julie, Goujon, Caroline, Joliot, Veronique, Briand, Pascale, Hazan, Uriel
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114953/
https://ncbi.nlm.nih.gov/pubmed/11333929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5425-5428.2001
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