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Structural Analysis of a Fiber-Pseudotyped Adenovirus with Ocular Tropism Suggests Differential Modes of Cell Receptor Interactions

Adenovirus (Ad) entry into cells is initiated by the binding of the fiber knob to a cell surface receptor. The coxsackie- and adenovirus receptor (CAR) functions as the attachment receptor for many, but not all, Ad serotypes. Ad type 37 (Ad37), a subgroup D virus that causes keratoconjunctivitis in...

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Main Authors: Chiu, Charles Y., Wu, Eugene, Brown, Swati L., Von Seggern, Dan J., Nemerow, Glen R., Stewart, Phoebe L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC114944/
https://ncbi.nlm.nih.gov/pubmed/11333920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5375-5380.2001
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