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Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism

Patients with Alzheimer's disease (AD) have abnormally low positron emission tomography (PET) measurements of the cerebral metabolic rate for glucose (CMRgl) in regions of the precuneus and the posterior cingulate, parietotemporal, and frontal cortex. Apolipoprotein E (APOE) ε4 gene dose (i.e.,...

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Hlavní autoři: Reiman, Eric M., Chen, Kewei, Alexander, Gene E., Caselli, Richard J., Bandy, Daniel, Osborne, David, Saunders, Ann M., Hardy, John
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149416/
https://ncbi.nlm.nih.gov/pubmed/15932949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500579102
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