Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism

Patients with Alzheimer's disease (AD) have abnormally low positron emission tomography (PET) measurements of the cerebral metabolic rate for glucose (CMRgl) in regions of the precuneus and the posterior cingulate, parietotemporal, and frontal cortex. Apolipoprotein E (APOE) ε4 gene dose (i.e.,...

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Detalhes bibliográficos
Main Authors: Reiman, Eric M., Chen, Kewei, Alexander, Gene E., Caselli, Richard J., Bandy, Daniel, Osborne, David, Saunders, Ann M., Hardy, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149416/
https://ncbi.nlm.nih.gov/pubmed/15932949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500579102
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