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5-Fluoromethylornithine, an irreversible and specific inhibitor of L-ornithine:2-oxo-acid aminotransferase.

5-Fluoromethylornithine (5-FMOrn) is the first specific irreversible inhibitor of L-ornithine:2-oxoacid aminotransferase (OAT) found. Single doses (greater than 10 mg/kg) of this compound inactivate OAT to a residual OAT-like activity. This activity (10-20% of total activity) is resistant to further...

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Bibliografiske detaljer
Main Authors: Daune, G, Gerhart, F, Seiler, N
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149323/
https://ncbi.nlm.nih.gov/pubmed/3178724
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