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Identification of Two Sequences in the Cytoplasmic Tail of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein That Inhibit Cell Surface Expression

During synthesis and export of protein, the majority of the human immunodeficiency virus type 1 (HIV-1) Env glycoprotein gp160 is retained in the endoplasmic reticulum (ER) and subsequently ubiquitinated and degraded by proteasomes. Only a small fraction of gp160 appears to be correctly folded and p...

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Autors principals: Bültmann, Andreas, Muranyi, Walter, Seed, Brian, Haas, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114932/
https://ncbi.nlm.nih.gov/pubmed/11333908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5263-5276.2001
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