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Release of copper from yeast copper-thionein after S-alkylation of copper-thiolate clusters.

Our knowledge on the release of copper from Cu-thionein in biological systems is limited. Other than oxidative cleavage or direct transfer, the possibility of an alkylation mechanism seemed attractive. Iodoacetamide and methyl methanesulphonate were successfully employed to alkylate the Cu-thiolate...

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Bibliographic Details
Main Authors: Felix, K, Weser, U
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149182/
https://ncbi.nlm.nih.gov/pubmed/3046608
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