Regulation of mRNA Translation and Cellular Signaling by Hepatitis C Virus Nonstructural Protein NS5A

The NS5A nonstructural protein of hepatitis C virus (HCV) has been shown to inhibit the cellular interferon (IFN)-induced protein kinase R (PKR). PKR mediates the host IFN-induced antiviral response at least in part by inhibiting mRNA translation initiation through phosphorylation of the α subunit o...

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Pubblicato in:	J Virol
Autori principali:	He, Yupeng, Tan, Seng-Lai, Tareen, Semih U., Vijaysri, Sangeetha, Langland, Jeffrey O., Jacobs, Bertram L., Katze, Michael G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11333890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.11.5090-5098.2001
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