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Interleukin-1 alpha modulates collagen gene expression in cultured synovial cells.

The effects of porcine interleukin-1 (IL-1) alpha on collagen production were studied in cultured human rheumatoid synovial cells. Addition of 0.05-5 ng of IL-1/ml into the cultures resulted in a dose-dependent decreased rate of collagen released into the medium over 24 h. To determine whether this...

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Detalhes bibliográficos
Main Authors: Mauviel, A, Teyton, L, Bhatnagar, R, Penfornis, H, Laurent, M, Hartmann, D, Bonaventure, J, Loyau, G, Saklatvala, J, Pujol, J P
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149130/
https://ncbi.nlm.nih.gov/pubmed/2844146
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