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Activation of TRAF5 and TRAF6 Signal Cascades Negatively Regulates the Latent Replication Origin of Epstein-Barr Virus through p38 Mitogen-Activated Protein Kinase

Latent Epstein-Barr virus (EBV) is maintained by the virus replication origin oriP that initiates DNA replication with the viral oriP-binding factor EBNA1. However, it is not known whether oriP's replicator activity is regulated by virus proteins or extracellular signals. By using a transient r...

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Detalhes bibliográficos
Main Authors: Shirakata, Masaki, Imadome, Ken-Ichi, Okazaki, Kenji, Hirai, Kanji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114910/
https://ncbi.nlm.nih.gov/pubmed/11333886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.11.5059-5068.2001
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