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Effect of oxygen concentration on microsomal oxidation of ethanol and generation of oxygen radicals.

The iron-catalysed production of hydroxyl radicals, by rat liver microsomes (microsomal fractions), assessed by the oxidation of substrate scavengers and ethanol, displayed a biphasic response to the concentration of O2 (varied from 3 to 70%), reaching a maximal value with 20% O2. The decreased rate...

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Detalhes bibliográficos
Main Authors: Puntarulo, S, Cederbaum, A I
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149072/
https://ncbi.nlm.nih.gov/pubmed/3415646
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