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Metabolites of procainamide and practolol inhibit complement components C3 and C4.

Drug-induced systemic lupus erythematosus arises from toxic side-effects of administration of hydralazine, isoniazid, procainamide and practolol. Hydralazine and isoniazid are nucleophilic drugs and inhibit the covalent binding reaction of complement components, C3 and C4, an effect likely to lead t...

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Bibliografiska uppgifter
Huvudupphovsmän: Sim, E, Stanley, L, Gill, E W, Jones, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149005/
https://ncbi.nlm.nih.gov/pubmed/2456755
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