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Herpesvirus Saimiri Open Reading Frame 50 (Rta) Protein Reactivates the Lytic Replication Cycle in a Persistently Infected A549 Cell Line

Herpesviruses occur in two distinct forms of infection, lytic replication and latent persistence. In this study, we investigated the molecular mechanisms that govern the latent-lytic switch in the prototype gamma-2 herpesvirus, herpesvirus saimiri (HVS). We utilized a persistently HVS-infected A549...

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Hlavní autoři: Goodwin, Delyth J., Walters, Matthew S., Smith, Peter G., Thurau, Mathias, Fickenscher, Helmut, Whitehouse, Adrian
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114895/
https://ncbi.nlm.nih.gov/pubmed/11264393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.4008-4013.2001
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