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Susceptibilities of lactoferrin and transferrin to myeloperoxidase-dependent loss of iron-binding capacity.

Apolactoferrin and apotransferrin lost their ability to subsequently bind iron when exposed to an excess of either HOCl or myeloperoxidase plus H2O2 and Cl-. Apolactoferrin, however, was more resistant than apotransferrin. By oxidizing a mixture of the two proteins, then separating them by immunopre...

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Autors principals: Winterbourn, C C, Molloy, A L
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148898/
https://ncbi.nlm.nih.gov/pubmed/2833250
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