Identification by fast atom bombardment mass spectrometry of insulin fragments produced by insulin proteinase.

We describe the isolation by reversed-phase h.p.l.c. of a number of products of the degradation of insulin by insulin proteinase and their direct analysis by fast atom bombardment mass spectrometry (f.a.b.-m.s.). Various semisynthetically labelled insulins were used, including [[2H2]GlyA1]insulin an...

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Auteurs principaux: Savoy, L A, Jones, R M, Pochon, S, Davies, J G, Muir, A V, Offord, R E, Rose, K
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148687/
https://ncbi.nlm.nih.gov/pubmed/3277618
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