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The dephosphorylation of inositol 1,4-bisphosphate to inositol in liver and brain involves two distinct Li+-sensitive enzymes and proceeds via inositol 4-phosphate.

1. Hydrolysis of both enantiomers of inositol 1-phosphate and both enantiomers of inositol 4-phosphate to inositol is inhibited by LiCl in liver and brain. 2. The phosphatase activity is predominantly soluble. 3. Inositol 1,4-bisphosphate is also hydrolysed by the soluble fraction of liver and brain...

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Bibliografische gegevens
Hoofdauteurs: Ragan, C I, Watling, K J, Gee, N S, Aspley, S, Jackson, R G, Reid, G G, Baker, R, Billington, D C, Barnaby, R J, Leeson, P D
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1988
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148677/
https://ncbi.nlm.nih.gov/pubmed/2829849
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