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Early conformational changes and activity modulation induced by guanidinium chloride on intestinal alkaline phosphatase.

Moderate concentrations of guanidinium chloride induce both instantaneous and time-dependent modifications of the catalytic and optical properties of intestinal alkaline phosphatase, which undergoes consecutive conformational transitions at about 0.05 M, 0.25 M and 1.0 M denaturant. A paradoxical ac...

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Detalhes bibliográficos
Main Authors: Miggiano, G A, Mordente, A, Pischiutta, M G, Martorana, G E, Castelli, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148577/
https://ncbi.nlm.nih.gov/pubmed/3435466
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